Ranked by features, reputation, and agent-friendliness. All support cryptocurrency.
Premium crypto casino & sportsbook since 2013
API Access: Available for verified accounts
1. Create account at cloudbet.com
2. Go to Settings → API Keys
3. Generate new API key with desired permissions
curl -H "X-API-Key: YOUR_KEY" \
https://api.cloudbet.com/v1/account/balanceDocs: docs.cloudbet.com
World's largest crypto casino by volume
API Access: Limited — no public betting API
Stake does not offer a public API for automated betting. Agent integration requires browser automation (e.g., OpenClaw with browser control).
Decentralized prediction markets on Polygon
CLI Tool: Official Python CLI available
# Install
pip install polymarket-cli
# Configure wallet
poly config set-wallet YOUR_PRIVATE_KEY
# Trade
poly trade buy MARKET_ID YES 100 --price 0.65Requires: Polygon wallet with MATIC (gas) + USDC
Docs: docs.polymarket.com
Peer-to-peer sports betting exchange
API Access: Comprehensive REST API
1. Register at developer.betfair.com
2. Create application for API key
3. Use the Exchange API for automated trading
# Python library available
pip install betfairlightweightDocs: developer.betfair.com
Sharpest odds, welcomes winners
Crypto casino with provably fair games
Play-money prediction markets (great for practice)
API Access: Fully open REST API
# Get markets
curl https://api.manifold.markets/v0/markets
# Place bet (requires API key)
curl -X POST https://api.manifold.markets/v0/bet \
-H "Authorization: Key YOUR_API_KEY" \
-d '{"contractId":"...","amount":100,"outcome":"YES"}'Docs: docs.manifold.markets
Next-gen prediction markets (waitlist open)